Article
[Molecular Features and Clinical Significance of Acute Myeloid Leukemia in Elderly Patients].
Zhongguo shi yan xue ye xue za zhi - 1 Oct 2020
Wang Bian-Hong, Guan Wei, Lyu Na, Jin Xiang-Shu, Li Ting, Yu Li, Jing Yu
Abstract excerpt
OBJECTIVE: To study the molecular characteristics and clinical significance of elderly patients with acute myeloid leukemia (AML). METHODS: Dideoxy sequencing was used to analyze the mutation spectrum and clinical significance of 51 hematopathy-related genes in 52 patients with newly diagnosed elderly AML. The efficacy of 39 patients receiving DCAG chemotherapy was also analyzed. RESULTS: The mutational frequency...
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