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Article

Mutation profile and prognostic relevance in elderly patients with de novo acute myeloid leukemia treated with decitabine-based chemotherapy.

International journal of laboratory hematology - 1 Dec 2020

Ni Jing, Hong Jian, Long Zhangbiao, Li Qingsheng, Xia Ruixiang, Zeng Qingshu

Abstract excerpt

INTRODUCTION: Decitabine-based chemotherapy regimens have shown efficacy in the treatment of elderly patients with acute myeloid leukemia (AML). However, it remains unclear whether any molecular alteration is correlated with the therapeutic effect of such treatment regimens. METHODS: Gene mutations were detected using next-generation sequencing, and their impact on survival was investigated in elderly AML...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32730663
DOI: 10.1111/ijlh.13299

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