Article
Genetic alterations and their clinical implications in older patients with acute myeloid leukemia.
Leukemia - 1 Jul 2016
Tsai Xavier Cheng-Hong, Hou H-A, Tang J-L, Liu C-Y, Lin C-C, Chou W-C, Tseng M-H, Chiang Y-C, Kuo Y-Y, Liu M-C, Liu C-W, Lin L-I, Tsay W, Yao M, Li C-C, Huang S-Y, Ko B-S, Hsu S-C, Chen C-Y, Lin C-T, Wu S-J, Tien H-F
Abstract excerpt
A number of patient-specific and leukemia-associated factors are related to the poor outcome in older patients with acute myeloid leukemia (AML). However, comprehensive studies regarding the impact of genetic alterations in this group of patients are limited. In this study, we compared relevant mutations in 21 genes between AML patients aged 60 years or older and those younger and exposed their prognostic...
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