Article
Characterization of Antigenic Relatedness between GII.4 and GII.17 Noroviruses by Use of Serum Samples from Norovirus-Infected Patients.
Journal of clinical microbiology - 1 Dec 2017
Dai Ying-Chun, Xia Ming, Huang Qiong, Tan Ming, Qin Lin, Zhuang Ya-Li, Long Yan, Li Jian-Dong, Jiang Xi, Zhang Xu-Fu
Abstract excerpt
A novel GII.17 norovirus variant caused major gastroenteritis epidemics in China in 2014 to 2016. To explore the host immune factors in selection of the emergence of this new variant, we characterized its antigenic relatedness with the GII.4 noroviruses that have dominated in China for decades. Through an enzyme-linked immunosorbent assay (ELISA) and a histo-blood group antigen (HBGA) blocking assay using sera...
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