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Article

Murine T-Helper Cell Differentiation and Plasticity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Siracusa Francesco, Muscate Franziska, Perez Laura Garcia

Abstract excerpt

CD4+ T helper (TH) cells are key mediators of immunity, and according to their effector functions, they can be divided into different subsets, namely, TH1, TH2, TH17, and TH22. In order to maintain systemic homeostasis and peripheral tolerance, CD4+ TH cells are counterbalanced by CD4+ T cells with regulatory properties, namely, Foxp3+ regulatory T cells (Foxp3+TREG) and TR1 cells. Here, we describe how to in...

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PMID: 33928543
DOI: 10.1007/978-1-0716-1311-5_5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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