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Article

Chromatin remodeling and T helper subset differentiation.

IUBMB life - 1 Jun 2000

Miyatake S, Arai N, Arai K

Abstract excerpt

The T helper subsets Th1 and Th2 regulate specific types of immune responses by producing distinct sets of cytokines. Differentiation of the T helper subsets from their common precursors, naive CD4+ T cells, is induced by antigen stimulation and controlled by various other conditions. Of these conditions, the contributions of the cytokine environment have been the best characterized. The presence of interleukin-4...

Topics

Alleles
Animals
Cell Differentiation
Chromatin
Gene Expression Regulation
Humans
Interleukins
Mice
Models, Genetic
Receptors, Cytokine
Signal Transduction
Th1 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Th2 Cells

Transcription Factors

Source

Identifiers

PMID: 11032239
DOI: 10.1080/15216540050166990

Genes

GATA3
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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