Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasticity of T-cell phenotype and function: the T helper type 17 example.

Immunology - 1 Feb 2010

Peck Ariana, Mellins Elizabeth D

Abstract excerpt

Mature T helper type 1 (Th1) and Th2 cells antagonize the development of the opposing subset to sustain lineage-specific responses. However, the recent identification of a third distinct subset of helper T cells - the Th17 lineage - collapses the established Th1/Th2 dichotomy and raises intriguing questions about T-cell fate. In this review, we discuss the Th17 subset in the context of the effector and regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to T-Lymphocytes, Regulatory
Share to Cell Differentiation
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon-gamma

Share to Interleukin-17

Share to T-bet Transcription Factor

Share to T-Box Domain Proteins

Share to T-Lymphocytes, Helper-Inducer

Source

Open in PubMed Open full text

Identifiers

PMID: 19922424
DOI: 10.1111/j.1365-2567.2009.03189.x
PMCID: PMC2814457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasticity of T-cell phenotype and function: the T helper type 17 example.PMID 19922424Read ↗

Identity crisis of Th17 cells: many forms, many functions, many questions.Semantic proximity Read ↗

Helper T cell diversity and plasticity.Semantic proximity Read ↗

Development and function of interleukin 17-producing γδ T cells.Semantic proximity Read ↗

[T(H)17 lymphocytes: induction, phenotype, functions, and implications in human disease and therapy].Semantic proximity Read ↗

The transient nature of the Th17 phenotypeSemantic proximity Read ↗

Murine T-Helper Cell Differentiation and Plasticity.Semantic proximity Read ↗

T cells in health and diseaseSemantic proximity Read ↗

Th17 plasticity: pathophysiology and treatment of chronic inflammatory disorders.Semantic proximity Read ↗

Th17 plasticity and its changes associated with inflammatory bowel disease.Semantic proximity Read ↗

Defining the human T helper 17 cell phenotype.Semantic proximity Read ↗

T helper 17 cell heterogeneity and pathogenicity in autoimmune disease.Semantic proximity Read ↗

Naturally arising memory-phenotype CD4+ T lymphocytes contain an undifferentiated population that can generate TH1, TH17, and Treg cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.