Stability and commitment in T helper cell development.

doi:10.1016/s0952-7915(00)00210-7

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Article

Stability and commitment in T helper cell development.

Current opinion in immunology - 1 Apr 2001

Asnagli H, Murphy K M

Abstract excerpt

Specialized effector activities that are required to eliminate various pathogens involve cytokines produced by specialized CD4(+) T cells subsets, dogmatically termed Th1 and Th2 cells. Despite some oversimplifications, this paradigm is useful for organizing the complex pathways that control forward and backward movements along the road of T cell differentiation. Effective immune memory relies, in part, on the...

Topics

Animals
Cell Differentiation
Humans
Interleukin-12
Interleukin-4
Phenotype
STAT6 Transcription Factor
Th1 Cells
Th2 Cells
Trans-Activators
Transcription Factors
Transcription, Genetic

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Open in PubMed

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PMID: 11228419
DOI: 10.1016/s0952-7915(00)00210-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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