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Article

Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing

22 Apr 2021

Abstract excerpt

BACKGROUND: Comprehensive and reliable drug susceptibility testing (DST) is urgently needed to provide adequate treatment regimens for patients with multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB). We determined whether next-generation sequencing (NGS) analysis of Mycobacterium tuberculosis complex isolates and genes implicated in drug resistance can guide the design of effective MDR/RR-TB...

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PMID: 33900387
DOI: 10.1093/cid/ciab359

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