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Article

Rapid drug resistance prediction in positive Mycobacterium tuberculosis clinical samples using an extensive targeted next-generation sequencing panel.

Emerging microbes & infections - 1 Dec 2026

Rosendal Ebba, Isidro Joana, Carneiro Sofia, Gomes João Paulo, Macedo Rita

Abstract excerpt

Tuberculosis (TB) remains a global health challenge, exacerbated by the emergence of drug-resistant Mycobacterium tuberculosis strains. Most methods for drug susceptibility testing (DST) are culture-dependent and time consuming, possibly delaying optimal TB-treatment. This study aimed to develop an extensive targeted next-generation sequencing (tNGS) approach for rapid genotypic DST directly from clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41631669
DOI: 10.1080/22221751.2026.2627072
PMCID: PMC12903939

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DST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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