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Article

Distinct TERT promoter C228T and C250T mutations in a patient with an oligodendroglioma: A case report.

Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Jun 2021

Ishi Yukitomo, Okada Hiromi, Okamoto Michinari, Motegi Hiroaki, Tanaka Shinya, Mitsuhashi Tomoko, Yamaguchi Shigeru

Abstract excerpt

The majority of oligodendroglial tumors harbor mutations in the telomerase reverse transcriptase (TERT) gene (TERT) promoter and the isocitrate dehydrogenase 1/2 (IDH1/2) gene (IDH1/2), as well as 1p/19q codeletion. Generally, TERT promoter mutations, C250T and C228T, are mutually exclusive. We present a case of oligodendroglioma harboring both C250T and C228T mutations in TERT promoter. A 38-year-old man...

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Identifiers

PMID: 33899270
DOI: 10.1111/neup.12727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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