Article
[Prognostic significance of combined TERT and IDH gene mutation analysis in diffusely infiltrating gliomas].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Sept 2018
Liu Q Q, Yin X X, Zou Y, Yu T P, Gong J, Chen X Q, Nie L, Xu M, Zhang M N, Zhou Q, Chen N
Abstract excerpt
Objective: To investigate the status and prognostic significance of TERT and IDH1/2 genes mutations in diffusely infiltrating gliomas. Methods: Hot spot mutations of TERT and IDH1/2 genes were detected by DNA sequencing in 236 cases of gliomas at West China Hospital from 2012 to 2016, including pilocytic astrocytoma (WHO grade Ⅰ, 16 cases), diffuse astrocytoma and oligodendroglioma (WHO grade Ⅱ, 89 cases),...
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