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Article

The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.

Acta neuropathologica communications - 29 Aug 2017

Lee Yujin, Koh Jaemoon, Kim Seong-Ik, Won Jae Kyung, Park Chul-Kee, Choi Seung Hong, Park Sung-Hye

Abstract excerpt

Mutations in the telomerase reverse transcriptase gene promoter (TERTp) are common in glioblastomas (GBMs) and oligodendrogliomas (ODGs), and therefore, have a key role in tumorigenesis and may be of prognostic value. However, the extent of their prognostic importance in various gliomas is controversial. We studied 168 patients separated into five groups: Group 1: 65 patients with ODG carrying an IDH1 or IDH2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28851427
DOI: 10.1186/s40478-017-0465-1
PMCID: PMC5574236

Genes

IDH1
IDH2
MGMT
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.PMID 28851427Read ↗

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