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Article

Interaction analysis of gene variants related to one-carbon metabolism with chronic hepatitis B infection in Chinese patients.

The journal of gene medicine - 1 Aug 2021

Sun Yao-Hui, Gao Jie, Liu Xu-Dong, Tang Hong-Wei, Cao Sheng-Li, Zhang Jia-Kai, Wen Pei-Hao, Wang Zhi-Hui, Li Jie, Guo Wen-Zhi, Zhang Shui-Jun

Abstract excerpt

BACKGROUND: The risk of chronic hepatitis B (CHB) infection is influenced by aberrant DNA methylation and altered nucleotide synthesis and repair, possibly caused by polymorphic variants in one-carbon metabolism genes. In the present study, we investigated the relationship between polymorphisms belonging to the one-carbon metabolic pathway and CHB infection. METHODS: A case-control study using 230 CHB patients...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Carbon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Modification Methylases

Share to DNA Repair Enzymes

Share to Glycine Hydroxymethyltransferase

Share to Hepatitis B, Chronic

Share to Methionine Adenosyltransferase

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Source

Identifiers

PMID: 33894044
DOI: 10.1002/jgm.3347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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