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Article

Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies

27 Feb 2022

Abstract excerpt

Primary prostate cancer (PCa) can show marked molecular heterogeneity. However, systematic analyses comparing primary PCa and matched metastases in individual patients are lacking. We aimed to address the molecular aspects of metastatic progression while accounting for the heterogeneity of primary PCa. In this pilot study, we collected 12 radical prostatectomy (RP) specimens from men who subsequently developed...

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PMID: 35220606
DOI: 10.1002/path.5887

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