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Article

Impact of Parkinson's disease risk loci on age at onset.

Movement disorders : official journal of the Movement Disorder Society - 1 May 2015

Lill Christina M, Hansen Johnni, Olsen Jørgen H, Binder Harald, Ritz Beate, Bertram Lars

Abstract excerpt

BACKGROUND: The aim of this study was to assess whether recently identified Parkinson's disease (PD) risk genes also influence age at onset in PD. METHODS: We genotyped 23 single-nucleotide polymorphisms in 1,526 Danish PD patients and performed linear regression analyses with age at onset. The combined impact of PD risk loci on age at onset was assessed by linear regression analyses using a weighted genetic risk...

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PMID: 25914293
DOI: 10.1002/mds.26237

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GAK

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