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[GO System, a DNA Repair Pathway to Cope with Oxidative Damage].

Molekuliarnaia biologiia - 1 Jan 2000

Endutkin A V, Zharkov D O

Abstract excerpt

The GO system is part of the DNA base excision repair pathway and is required for the error-free repair of 8-oxoguanine (oxoG), one of the most common oxidative DNA lesions. Due to the ability of oxoG to form oxoG:A mispairs, this base is highly mutagenic. Its repair requires the action of two enzymes: 8-oxoguanine DNA glycosylase (Fpg or MutM in bacteria and OGG1 in eukaryotes), which removes oxoG from oxoG:C...

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Identifiers

PMID: 33871437
DOI: 10.31857/S0026898421020063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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