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Article

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine.

DNA repair - 4 Jun 2010

van Loon Barbara, Markkanen Enni, Hübscher Ulrich

Abstract excerpt

The maintenance of genetic stability is of crucial importance for any form of life. Prior to cell division in each mammalian cell, the process of DNA replication must faithfully duplicate the three billion bases with an absolute minimum of mistakes. Various environmental and endogenous agents, such as reactive oxygen species (ROS), can modify the structural properties of DNA bases and thus damage the DNA. Upon...

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Identifiers

PMID: 20399712
DOI: 10.1016/j.dnarep.2010.03.004

Genes

MUTYH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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