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Article

[The role of glycosylases of the base excision DNA repair in pathogenesis of hereditary and infectious human diseases].

Molekuliarnaia biologiia - 1 Jan 2000

Sidorenko V S, Zharkov D O

Abstract excerpt

DNA glycosylases are enzymes that initiate base excision repair, a process of removal of damaged bases from the cellular DNA. Recent data show that variants of two human DNA glycosylases, MUTYH and OGG1, are associated with an increased risk of cancer. In addition, activities of various DNA glycosylases have been implicated in protection of humans from neurodegenerative diseases, immune disorders and viral...

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Source

Identifiers

PMID: 18988537

Genes

MUTYH
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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