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Article

AML-Associated Mutations in DNA Methyltransferase DNMT3A.

Biochemistry. Biokhimiia - 1 Mar 2021

Khrabrova Dariya A, Yakubovskaya Marianna G, Gromova Elizaveta S

Abstract excerpt

In mammals, DNA methylation is an essential epigenetic modification necessary for the maintenance of genome stability, regulation of gene expression, and other processes. Carcinogenesis is accompanied by multiple changes in the DNA methylation pattern and DNA methyltransferase (DNMT) genes; these changes are often associated with poor disease prognosis. Human DNA methyltransferase DNMT3A is responsible for de...

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Identifiers

PMID: 33838631
DOI: 10.1134/S000629792103007X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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