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Article

Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression.

Human molecular genetics - 26 Jun 2021

Pathak Gita A, Wendt Frank R, Levey Daniel F, Mecca Adam P, van Dyck Christopher H, Gelernter Joel, Polimanti Renato

Abstract excerpt

Several studies have reported association between leukocyte telomere length (LTL) and neuropsychiatric disorders. Although telomere length is affected by environmental factors, genetic variants in certain loci are strongly associated with LTL. Thus, we aimed to identify the genomic relationship between genetic variants of LTL with brain-based regulatory changes and brain volume. We tested genetic colocalization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33831179
DOI: 10.1093/hmg/ddab102
PMCID: PMC8255129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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