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Unraveling the causal genes and transcriptomic determinants of human telomere length

21 Dec 2023

Abstract excerpt

Telomere length (TL) shortening is a pivotal indicator of biological aging and is associated with many human diseases. The genetic determinates of human TL have been widely investigated, however, most existing studies were conducted based on adult tissues which are heavily influenced by lifetime exposure. Based on the analyses of terminal restriction fragment (TRF) length of telomere, individual genotypes, and...

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PMID: 38129441
DOI: 10.1038/s41467-023-44355-z

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