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Article

Telomere length and brain imaging phenotypes in UK Biobank.

PloS one - 1 Jan 2023

Topiwala Anya, Nichols Thomas E, Williams Logan Z J, Robinson Emma C, Alfaro-Almagro Fidel, Taschler Bernd, Wang Chaoyue, Nelson Christopher P, Miller Karla L, Codd Veryan, Samani Nilesh J, Smith Stephen M

Abstract excerpt

Telomeres form protective caps at the ends of chromosomes, and their attrition is a marker of biological aging. Short telomeres are associated with an increased risk of neurological and psychiatric disorders including dementia. The mechanism underlying this risk is unclear, and may involve brain structure and function. However, the relationship between telomere length and neuroimaging markers is poorly...

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Identifiers

PMID: 36947528
DOI: 10.1371/journal.pone.0282363
PMCID: PMC10032499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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