Article
Aggressive organ penetration and high vector transmissibility of epidemic dengue virus-2 Cosmopolitan genotype in a transmission mouse model.
PLoS pathogens - 1 Mar 2021
Lin Jhe-Jhih, Chung Pei-Jung, Dai Shih-Syong, Tsai Wan-Ting, Lin Yu-Feng, Kuo Yi-Ping, Tsai Kuen-Nan, Chien Chia-Hao, Tsai De-Jiun, Wu Ming-Sian, Shu Pei-Yun, Yueh Andrew, Chen Hsin-Wei, Chen Chun-Hong, Yu Guann-Yi
Abstract excerpt
Dengue virus (DENV) causes dengue fever and severe hemorrhagic fever in humans and is primarily transmitted by Aedes aegypti and A. albopictus mosquitoes. The incidence of DENV infection has been gradually increasing in recent years due to global urbanization and international travel. Understanding the virulence determinants in host and vector transmissibility of emerging epidemic DENV will be critical to combat...
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