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Article

Distinct genomic features across cytolytic subgroups in skin melanoma.

Cancer immunology, immunotherapy : CII - 1 Nov 2021

Roufas Constantinos, Georgakopoulos-Soares Ilias, Zaravinos Apostolos

Abstract excerpt

BACKGROUND: Skin melanoma is a highly immunogenic cancer. The intratumoral immune cytolytic activity (CYT) reflects the ability of cytotoxic T and NK cells to eliminate cancer cells, and is associated with improved patient survival. Despite the enthusiastic clinical results seen in advanced-stage metastatic melanoma patients treated with immune checkpoint inhibitors, a subgroup of them will later relapse and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33779796
DOI: 10.1007/s00262-021-02918-3
PMCID: PMC8505325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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