Article
Genetic Predisposition to Type 2 Diabetes and Insulin Levels Is Positively Associated With Serum Urate Levels.
The Journal of clinical endocrinology and metabolism - 16 Jun 2021
Zhu Jiahao, Sun Lingling, Yang Jing, Fan Jiayao, Tse Lap Ah, Li Yingjun
Abstract excerpt
PURPOSE: Previous epidemiological evidence showed that type 2 diabetes (T2D) is related with gout. However, the causality and the direction of this association are still not definitely elucidated. We investigated bidirectional associations of T2D and glycemic traits with serum urate concentrations and gout using a Mendelian randomization approach. METHODS: Summary statistics from the large-scale genomewide...
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