Article
Association between plasma uric acid and insulin resistance in type 2 diabetes: A Mendelian randomization analysis.
Diabetes research and clinical practice - 1 Jan 2021
Hu Xueting, Rong Shuang, Wang Qiang, Sun Taoping, Bao Wei, Chen Liangkai, Liu Liegang
Abstract excerpt
OBJECTIVE: Circulating uric acid levels were associated with insulin resistance, but the causality is unclear. We aimed to investigate the association between plasma uric acid and insulin resistance in newly diagnosed type 2 diabetes (T2D). METHODS: We enrolled 1,938 patients who underwent a 75-g oral glucose tolerance test. Insulin resistance was estimated based on the homeostatic model assessment index...
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