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TGFβ/BMP Signaling Pathway in Cartilage Homeostasis

24 Aug 2019

Abstract excerpt

Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate extracellular matrix production and degradation. In turn, chondrocyte activity is regulated by growth factors such as those of the transforming growth factor β (TGFβ) family. Members of this family include the TGFβs, bone morphogenetic proteins (BMPs), and growth and differentiation factors (GDFs). Signaling by this protein...

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PMID: 31450621
DOI: 10.3390/cells8090969

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