Article

BMP signaling: A significant player and therapeutic target for osteoarthritis

2021-03-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To investigate the role of BMP signaling in osteoarthritis' pathogenesis and propose a disease-modifying therapy for OA. <h4>Methods</h4> C57BL6/J mouse line was used to perform ACLT surgery at P120 to study the expression pattern of the BMP signaling readout pSMAD1/5/9. To investigate whether activation of BMP signaling is sufficient and necessary to induce osteoarthritis,...

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Literature Corpus work: d365b8e8-2d90-5c53-b2ee-5a08f7369a0a
DOI: 10.1101/2021.03.01.433366

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