Article
[Detection of PIK3CA gene mutation and its related prognosis in colorectal cancer based on next-generation sequencing].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Jul 2024
Peng X, Zhang X, Lu H X, Shen L L, Gao N, Zan L K
Abstract excerpt
Objectives: To investigate the mutation of PIK3CA in colorectal cancer and to analyze their clinicopathological features, and evaluate their role in clinical treatment and prognostication. Methods: A total of 128 paraffin-embbeded tissue samples of colorectal cancer from Shanxi Cancer Hospital from 2018 to 2021 were collected. DNA was extracted from the samples, and next-generation sequencing (NGS) was used to...
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