Article
Pediatric Non-Alcoholic Fatty Liver Disease Is Affected by Genetic Variants Involved in Lifespan/Healthspan.
Journal of pediatric gastroenterology and nutrition - 1 Aug 2021
Crudele Annalisa, Dato Serena, Re Oriana Lo, Maugeri Andrea, Sanna Paola, Giallongo Sebastiano, Oben Jude, Panera Nadia, De Rango Francesco, Mosca Antonella, Rose Giuseppina, Passarino Giuseppe, Alisi Anna, Vinciguerra Manlio
Abstract excerpt
OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in both adults and children. Along with obesity and metabolic syndrome, genetic predisposition influences the progression of NAFLD. Here, we investigated the effect of lifespan/healthspan-related single nucleotide polymorphisms (SNPs) on metabolically associated fatty liver disease in children. METHODS: We...
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