Article
Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology.
Nature reviews. Gastroenterology & hepatology - 1 Jan 2020
Eslam Mohammed, George Jacob
Abstract excerpt
Nonalcoholic fatty liver disease (NAFLD) affects around a quarter of the global population, paralleling worldwide increases in obesity and metabolic syndrome. NAFLD arises in the context of systemic metabolic dysfunction that concomitantly amplifies the risk of cardiovascular disease and diabetes. These interrelated conditions have long been recognized to have a heritable component, and advances using unbiased...
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