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Article

Human Genetics to Identify Therapeutic Targets for NAFLD: Challenges and Opportunities.

Frontiers in endocrinology - 1 Jan 2021

Du Xiaomi, DeForest Natalie, Majithia Amit R

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is a continuous progression of pathophysiologic stages that is challenging to diagnose due to its inherent heterogeneity and poor standardization across a wide variety of diagnostic measures. NAFLD is heritable, and several loci have been robustly associated with various stages of disease. In the past few years, larger genetic association studies using new methodology...

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Identifiers

PMID: 34950105
DOI: 10.3389/fendo.2021.777075
PMCID: PMC8688763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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