Article
NK1.1- natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis.
American journal of physiology. Renal physiology - 1 May 2021
An Jung Nam, Ryu Seungwon, Kim Yong Chul, Yoo Kyung Don, Lee Jangwook, Kim Hye Young, Lee Hajeong, Lee Jung Pyo, Lee Jae Wook, Jeon Un Sil, Kim Dong Ki, Kim Yon Su, Yang Seung Hee
Abstract excerpt
Interleukin (IL)-17-secreting invariant natural killer T (NKT) cells are involved in several inflammatory diseases. However, their role in lupus nephritis (LN) has not been fully characterized. Samples from patients with LN or glomerulonephritis and healthy controls were obtained, and elevated IL-17+ NKT cell numbers and IL-17 expression were observed in blood cells and kidneys, respectively, in patients with LN....
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