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Article

Insight Into Non-Pathogenic Th17 Cells in Autoimmune Diseases.

Frontiers in immunology - 1 Jan 2018

Wu Xinyu, Tian Jie, Wang Shengjun

Abstract excerpt

Th17 cells are generally considered to be positive regulators of immune responses because they produce pro-inflammatory cytokines, including IL-17A, IL-17F, and IL-22. Cytokine production not only promotes accumulation of immune cells, such as macrophages, neutrophils and lymphocytes, at inflammatory sites but can also cause tissue pathologies. Conversely, certain Th17 cells can also negatively regulate immune...

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Identifiers

PMID: 29892286
DOI: 10.3389/fimmu.2018.01112
PMCID: PMC5985293

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