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DNA damage response as a prognostic indicator in metastatic breast cancer via mutational analysis

1 Feb 2021

Abstract excerpt

Background: High tumor heterogeneity contributes to breast cancer recurrence and metastasis. However, the lack of indicators to serve as precise and reliable means of predicting breast cancer prognosis has yet to be addressed. This study aims to reveal the prognostic relevance of mutations in metastatic breast cancer (MBC) by large-scale circulating tumor DNA (ctDNA) analysis in China. Methods: We performed ctDNA...

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Breast Cancer Treatment Studies
Cancer Genomics and Diagnostics
PARP inhibition in cancer therapy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33708847
DOI: 10.21037/atm-20-2137

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