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Article

Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2021

Akcakanat Argun, Zheng Xiaofeng, Cruz Pico Christian X, Kim Tae-Beom, Chen Ken, Korkut Anil, Sahin Aysegul, Holla Vijaykumar, Tarco Emily, Singh Gopal, Damodaran Senthil, Mills Gordon B, Gonzalez-Angulo Ana Maria, Meric-Bernstam Funda

Abstract excerpt

PURPOSE: Metastatic breast cancer (MBC) is not curable and there is a growing interest in personalized therapy options. Here we report molecular profiling of MBC focusing on molecular evolution in actionable alterations. EXPERIMENTAL DESIGN: Sixty-two patients with MBC were included. An analysis of DNA, RNA, and functional proteomics was done, and matched primary and metastatic tumors were compared when feasible....

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Identifiers

PMID: 33782032
DOI: 10.1158/1078-0432.CCR-20-4048
PMCID: PMC8172429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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