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Survival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer

24 Apr 2018

Abstract excerpt

Purpose To determine the significant genomic alterations in patients with metastatic breast cancer (MBC) and survival outcomes in common genotypes. Patients and Methods High-depth next-generation sequencing was performed for 202 genes in tumor and normal DNA from 257 patients with MBC, including 165 with estrogen receptor/progesterone receptor–positive and human epidermal growth factor receptor 2 (HER2 [hormone...

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PMID: 30035249
DOI: 10.1200/po.17.00245

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