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Article

Clinical spectrum and prognostic value of TP53 mutations in circulating tumor DNA from breast cancer patients in China.

Cancer communications (London, England) - 1 Jun 2020

Yi Zongbi, Ma Fei, Rong Guohua, Guan Yanfang, Li Chunxiao, Xu Binghe

Abstract excerpt

BACKGROUND: TP53 mutations are common in breast cancer. There is currently no large-scale cohort study to investigate the TP53 landscape in breast cancer patients from China. The predictive value of TP53 mutations for the efficacy of human epidermal growth factor receptor 2 (HER2)-targeted therapy in breast cancer remains controversial. In the present study, we aimed to analyze the clinical spectrum and...

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Identifiers

PMID: 32436611
DOI: 10.1002/cac2.12032
PMCID: PMC7307233

Genes

TP53

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