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Prognostic analysis of patients with breast cancer based on tumor mutational burden and DNA damage repair genes

7 Jun 2023

Abstract excerpt

Background: Breast cancer has a high tumor-specific death rate and poor prognosis. In this study, we aimed to provide a basis for the prognostic risk in patients with breast cancer using significant gene sets selected by analyzing tumor mutational burden (TMB) and DNA damage repair (DDR). Methods: Breast cancer genomic and transcriptomic data were obtained from The Cancer Genome Atlas (TCGA). Breast cancer...

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PMID: 37350936
DOI: 10.3389/fonc.2023.1177133

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