Article
Identification & characterization of leucine-rich repeat kinase 2 & parkin RBR E3 ubiquitin protein ligase variants in patients with Parkinson's disease.
The Indian journal of medical research - 1 Nov 2020
Halder Tamali, Verma Shiv Prakash, Raj Janak, Pandey Sharad, Singh Ranjeet Kumar, Sharma Vivek, Joshi Deepika, Das Parimal
Abstract excerpt
BACKGROUND & OBJECTIVES: Parkinson's disease (PD) is a motor disorder that affects movement. More than 24 loci and 28 associated genes have been identified to be associated with this disease. The present study accounts for the contribution of two candidates, leucine-rich repeat kinase 2 ( LRRK2) and parkin RBR E3 ubiquitin protein ligase ( PRKN) in the PD patients, and their characterization in silico and in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.