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Article

Somatic Genetic Mosaicism in the Apolipoprotein E-null Mouse Aorta.

Thrombosis and haemostasis - 1 Nov 2021

Valencia-Morales María Del Pilar, Sanchez-Flores Alejandro, Colín-Castelán Dannia, Alvarado-Caudillo Yolanda, Fragoso-Bargas Nicolás, López-González Gladys, Peña-López Tania, Ramírez-Nava Magda, de la Rocha Carmen, Rodríguez-Ríos Dalia, Lund Gertrud, Zaina Silvio

Abstract excerpt

In addition to genetic and epigenetic inheritance, somatic variation may contribute to cardiovascular disease (CVD) risk. CVD-associated somatic mutations have been reported in human clonal hematopoiesis, but evidence in the atheroma is lacking. To probe for somatic variation in atherosclerosis, we sought single-nucleotide private variants (PVs) in whole-exome sequencing (WES) data of aorta, liver, and skeletal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 33677828
DOI: 10.1055/a-1414-4840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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