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Myocyte Enhancer Factor 2C as a New Player in Human Breast Cancer Brain Metastases

12 Feb 2021

Abstract excerpt

Myocyte enhancer factor 2C (MEF2C) is increasingly expressed in mice along with breast cancer brain metastases (BCBM) development. We aim to ascertain MEF2C expression in human BCBM, establish the relationship with disease severity, disclose the involvement of vascular endothelial growth factor receptor-2 (VEGFR-2) and β-catenin, also known as KDR and CTNNB1, respectively, and investigate if matched primary...

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PMID: 33673112
DOI: 10.3390/cells10020378

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