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Gene Expression Profiling of Breast Cancer Brain Metastasis

24 Jun 2016

Abstract excerpt

The biology of breast cancer brain metastasis (BCBM) is poorly understood. We aimed to explore genes that are implicated in the process of brain metastasis of primary breast cancer (BC). NanoString nCounter Analysis covering 252 target genes was used for comparison of gene expression levels between 20 primary BCs that relapsed to brain and 41 BCBM samples. PAM50-based intrinsic subtypes such as HER2-enriched and...

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PMID: 27340107
DOI: 10.1038/srep28623

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