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Article

Molecular characterization of breast cancer CTCs associated with brain metastasis

28 Jul 2017

Abstract excerpt

The enumeration of EpCAM-positive circulating tumor cells (CTCs) has allowed estimation of overall metastatic burden in breast cancer patients. However, a thorough understanding of CTCs associated with breast cancer brain metastasis (BCBM) is necessary for early identification and evaluation of treatment response to BCBM. Here we report that BCBM CTCs is enriched in a distinct sub-population of cells identifiable...

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PMID: 28775303
DOI: 10.1038/s41467-017-00196-1

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