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Article

Imaging tau burden in dementia with Lewy bodies using [18F]-AV1451 positron emission tomography.

Neurobiology of aging - 1 May 2021

Mak Elijah, Nicastro Nicolas, Malpetti Maura, Savulich George, Surendranathan Ajenthan, Holland Negin, Passamonti Luca, Jones P Simon, Carter Stephen F, Su Li, Hong Young T, Fryer Tim D, Williams Guy B, Aigbirhio Franklin, Rowe James B, O'Brien John T

Abstract excerpt

Alzheimer's disease (AD) pathology is frequently observed as a comorbidity in people with dementia with Lewy bodies (DLB). Here, we evaluated the in vivo distribution of tau burden and its influence on the clinical phenotype of DLB. Tau deposition was quantified using [18F]-AV1451 positron emission tomography in people with DLB (n = 10), AD (n = 27), and healthy controls (n = 14). A subset of patients with Lewy...

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Identifiers

PMID: 33631469
DOI: 10.1016/j.neurobiolaging.2020.11.006
PMCID: PMC8209140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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