Article

<i>In vivo</i> PET imaging of neuroinflammation in familial frontotemporal dementia

2020-05-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> We report in vivo patterns of neuroinflammation and abnormal protein aggregation in seven cases of familial frontotemporal dementia with mutations in MAPT, GRN and C9orf72 genes. <h4>METHODS</h4> Using positron emission tomography (PET), we explored the association of the distribution of activated microglia, as measured by the radioligand [ 11 C]PK11195, and the regional dis...

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Literature Corpus work: 76e5007c-8d8f-509d-b605-4024b76db3ed
DOI: 10.1101/2020.05.11.20098046

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