Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Donor UNC-93 Homolog B1 genetic polymorphism predicts survival outcomes after unrelated bone marrow transplantation.

Genes and immunity - 1 May 2021

Uchino Kaori, Vu Quang Lam, Mizuno Shohei, Horio Tomohiro, Yamamoto Hidesuke, Hanamura Ichiro, Kodera Yoshihisa, Luis Espinoza J, Onizuka Makoto, Kashiwase Koichi, Morishima Yasuo, Fukuda Takahiro, Doki Noriko, Miyamura Koichi, Mori Takehiko, Morishita Eriko, Nakao Shinji, Takami Akiyoshi

Abstract excerpt

UNC-93 homolog B1 (UNC93B1) is a key regulator of toll-like receptors (TLRs), pattern recognition receptors that sense invading pathogens and manage the innate immune response and deliver them from the endoplasmic reticulum to their respective endosomal signaling compartments. Several types of TLRs are known to contribute to the inflammatory process after allogeneic hematopoietic stem cell transplantation (SCT),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematologic Neoplasms

Share to Hematopoietic Stem Cell Transplantation

Share to Membrane Transport Proteins

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 33627833
DOI: 10.1038/s41435-021-00122-y
PMCID: PMC7903020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Donor UNC-93 Homolog B1 genetic polymorphism predicts survival outcomes after unrelated bone marrow transplantation.PMID 33627833Read ↗

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation.Semantic proximity Read ↗

Genetic variants of human granzyme B predict transplant outcomes after HLA matched unrelated bone marrow transplantation for myeloid malignancies.Semantic proximity Read ↗

Recipient PTPN22 -1123 C/C genotype predicts acute graft-versus-host disease after HLA fully matched unrelated bone marrow transplantation for hematologic malignancies.Semantic proximity Read ↗

Toll-like receptor 1 variation increases the risk of transplant-related mortality in hematologic malignancies.Semantic proximity Read ↗

Toll-like receptor genetic variations in bone marrow transplantation.Semantic proximity Read ↗

MHC-resident variation affects risks after unrelated donor hematopoietic cell transplantation.Semantic proximity Read ↗

Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus.Semantic proximity Read ↗

Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosusSemantic proximity Read ↗

Multiple single-nucleotide polymorphism-based risk model for clinical outcomes after allogeneic stem-cell transplantation, especially for acute graft-versus-host disease.Semantic proximity Read ↗

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia.Semantic proximity Read ↗

Donor KIR3DL1/3DS1 Gene and Recipient Bw4 KIR Ligand as Prognostic Markers for Outcome in Unrelated Hematopoietic Stem Cell TransplantationSemantic proximity Read ↗

Variants Affecting the C-Terminal Tail of UNC93B1 Are Not a Common Risk Factor for Systemic Lupus Erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.