Article
Toll-like receptor genetic variations in bone marrow transplantation.
Oncotarget - 11 Jul 2017
Uchino Kaori, Mizuno Shohei, Sato-Otsubo Aiko, Nannya Yasuhito, Mizutani Motonori, Horio Tomohiro, Hanamura Ichiro, Espinoza J Luis, Onizuka Makoto, Kashiwase Koichi, Morishima Yasuo, Fukuda Takahiro, Kodera Yoshihisa, Doki Noriko, Miyamura Koichi, Mori Takehiko, Ogawa Seishi, Takami Akiyoshi
Abstract excerpt
The Toll-like receptor family mediates the innate immune system through recognizing the molecular patterns of microorganisms and self-components and leading the synthesis of the inflammatory mediators. We retrospectively examined whether or not genetic variations in toll-like receptor 1 (rs5743551, -7202GQ>A), toll-like receptor 2 (rs7656411, 22215G>T), and toll-like receptor 4 (rs11536889, +3725G>C) affected...
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