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Article

Catalytic Cross Talk between Key Peptide Fragments That Couple Alzheimer's Disease with Amyotrophic Lateral Sclerosis.

Journal of the American Chemical Society - 10 Mar 2021

Laos Veronica, Bishop Dezmond, Ganguly Pritam, Schonfeld Grace, Trapp Ellen, Cantrell Kristi Lazar, Buratto Steven K, Shea Joan-Emma, Bowers Michael T

Abstract excerpt

Protein aggregation is a common feature in prominent neurodegenerative diseases, usually thought to be due to the assembly of a single peptide or protein. Recent studies have challenged this notion and suggested several proteins may be involved in promoting and amplifying disease. For example, the TDP-43 protein associated with Amyotrophic Lateral Sclerosis has been found in the brain along with Aβ assemblies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33621087
DOI: 10.1021/jacs.0c12729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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